Mission

ICER's mission is to lead innovation in comparative effectiveness research through methods that integrate considerations of clinical benefit and economic value.  Through a unique collaboration with patients, clinicians, manufacturers, insurers and other healthcare stakeholders, ICER develops tools to support patient decisions and medical policy that share the goal of achieving maximum value for every healthcare dollar.

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IMRT for Localized Prostate Cancer

IMRT is a form of external beam radiation therapy that uses multiple beam angles and non-uniform beam intensities along with CT based computer planning to conform the radiation to the target organ in order to spare normal adjacent structures.  IMRT thus has many similarities with three dimensional conformal radiation therapy (3D-CRT) which also uses CT imaging to construct 3D images to help maintain full dose to the target organ while decreasing the radiation dose to normal tissue.  The basic premise underlying the potential advantages of IMRT over 3D-CRT is that sculpting the radiation to the target volume of the cancer more precisely will result in:

  • A reduction in acute toxicity to the surrounding normal tissues of the gastrointestinal (GI), genitourinary (GU) and sexual organs
  • The ability to increase the dose to the tumor target, thus potentially reducing local recurrence rates.

 

Background Materials
IMRT Evidence Review Group

 

Draft Appraisal Documents

ICER Evidence Review Group Introductory Slides

IMRT Side Effects Economic Model Slides

 

 Final Appraisal Documents

IMRT Final Apprasial -- Executive Summary

IMRT Final Appraisal -- Full Report 

 

 

Comments on ICER report from Radiation Therapy Alliance (RTA)

 

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