Mission

ICER's mission is to lead innovation in comparative effectiveness research through methods that integrate considerations of clinical benefit and economic value.  Through a unique collaboration with patients, clinicians, manufacturers, insurers and other healthcare stakeholders, ICER develops tools to support patient decisions and medical policy that share the goal of achieving maximum value for every healthcare dollar.

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Marc D. Silverstein, MD FACP
Chief Decision Scientist


Dr. Silverstein is the Chief Decision Scientist at the Institute for Clinical and Economic Review and works on developing and executing the economic modeling for ICER’s comparative effectiveness appraisals.  Dr. Silverstein brings over two decades of experience in medicine, clinical epidemiology and decision sciences to ICER.

Dr. Silverstein has worked most recently as an independent health services research consultant at Health Care Research, specializing in health economics, decision analysis and cost-effectiveness research.  In 2006-2007 he served as Chairman of the Department of Public Health at the Methodist Hospital in Houston and was Professor of Medicine and Public Health at the Weill Cornell Medical College.  Earlier in his career, Dr. Silverstein held positions as a Career Scientist at the Mayo Clinic, and Director of the Center for Health Care Research and Professor of General Internal Medicine, Biometry and Epidemiology at the Medical University of South Carolina.  Dr. Silverstein’s research interests have focused on outcomes research, technology assessment, and the cost-effectiveness of preventive services.  

Dr. Silverstein received his SB from the Massachusetts Institute of Technology and his MD from the Columbia University College of Physicians and Surgeons.  Following medical school, Dr. Silverstein completed his residency training in internal medicine at the New York University Bellevue Hospital Medical Center in New York and was a Henry J. Kaiser Fellow in General Internal Medicine at the Massachusetts General Hospital.  He is Board Certified in Internal Medicine, with certificates of added qualification in Critical Care Medicine and in Geriatrics.  Dr. Silverstein has served as a member of the research review committees for the National Institutes of Health, the Agency for Healthcare Research and Quality, the Veterans Administration, and the Centers for Medicare and Medicaid Services.  Dr. Silverstein has been principal investigator of research grants from the National Institutes of Health and industry.  Dr. Silverstein is the author of over 100 peer-reviewed articles.


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